Bruger:Drlectin/sandkasse4: Forskelle mellem versioner
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Drlectin (diskussion | bidrag) No edit summary |
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Linje 9:
Der kendes mere end 750 proteiner med fra et til 112 immunoglobulinlignende domæner
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/immunoglobulin-
Et immunglobulinlignende domæne består typisk af 70-100 [[aminosyre]]r arrangeret i en sandwich af to beta-sheets med 7-9 beta-kæder i et fast [[meander]]-mønster (se billedet<ref>[https://www.cell.com/fulltext/S0969-2126%2899%2980181-6 Folding studies of immunoglobulin-like β-sandwich proteins suggest that they share a common folding pathway. Cell Press 1999]</ref>).
Linje 301:
* E. coli methionine ABC transporter - usædvanligt da de fleste ABC transportere har 6 TMD.
* YIPF-proteiner, lokaliseret først og fremmest i [[Golgi]] [https://www.frontiersin.org/articles/10.3389/fcell.2019.00130/full Characteristics and Functions of the Yip1 Domain Family (YIPF), Multi-Span Transmembrane Proteins Mainly Localized to the Golgi Apparatus. REVIEW ARTICLE. Front. Cell Dev. Biol., 30 July 2019]
=== 4TMD ===
Line 328 ⟶ 330:
* TMEM258 subunit af STT3A/OST complex og af STT3B/OST complex [https://www.mdpi.com/1422-0067/20/23/6074/htm]
=== 1TMD homodimere ===
* Cytokine receptors [https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1002427]
** GHR, growth hormone receptor
** PRLR, prolaktin receptor
** EPOR, erythropoietin receptor
* Currently available homodimer structures of mammalian WT SPTMR‐TMDs.[https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.13793]
** APP, amyloid precursor protein
** TLR3, Toll‐like receptor 3
** GpA, glycophorin A
** EphA1 og EphA2, ephrin receptor
** ErbB1, ErbB2, ErbB3 og ErbB4, epidermal growth factor receptor
** VEGFR2, vascular endothelium growth factor receptor 2
** PDGFR, platelet‐derived growth factor receptor
** FGFR3, fibroblast growth factor receptor
** ζζ
** DAP12, lymphoid/myeloid receptor signaling module
=== 1TMD ===
Type I (single pass) https://en.m.wikipedia.org/wiki/Membranome_database https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/single-pass-transmembrane-proteins▼
Type I (single pass)
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.13793
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* Neuropilin-1, værtsreceptor for [[SARS-CoV-2]].<ref>[https://science.sciencemag.org/content/early/2020/10/19/science.abd2985 Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity. Science 2020]</ref>
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